From the Joy of Apple
Are you stuck trying to decide which IRC client is the best for you? To help make the job easier for you, I have reviewed all of the most popular IRC clients for OS X here, listing their pros and cons and including screenshots. I have tried virtually all the clients available for OS X and finally selected one. This is my list of reviews of the various IRC clients available at the moment. From best to worst.
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WSOP event recaps, poker strategy articles, site reviews for PokerStars and Full Tilt Poker, and everything else you'll need to play Mac poker is at MacPoker.net!
3rd Light Digital Media
Also, there's IRC chat at irc.netmug.org, channel #yourmaclife. We look forward to seeing you!
Lesa's Pick
Sly's Pick
Congratulations - you found it! We cleverly hid it way down here...
Click here to listen - On this week's show: 
They've forgotten an amazing
They've forgotten an amazing client (in my opinion); X-Chat Aqua. It's a port of the Windows version (X-Chat)
http://sourceforge.net/projects/xchataqua/
:)
--
Ian Nixon
iannixon.com