Mozyhome or JungleDisk and S3 with Apple's Backup (or another backup program)?

Anyone tried either of those? Any other solutions? Opinions? Pros and cons? Is Apple's Backup app up to the task if I go with JungleDisk and S3? Or what app did you use instead? How does JungleDisk work exactly? What sort of drive appears? Limitations?

In case anyone else wonders - Mozy is backup with online storage included, and JungleDisk is a way to have Amazon's S3 online storage service appear on the desktop as a drive.

Your help is REALLY appreciated as I'm in dire need of a decent online backup strategy for a new Mac that will be storing some very important data. I'm already using Time Machine with an external HD, but of course that does no good if the house burns down.

TIA,
Jamie Kahn Genet